Cottonmouth is a city in Manhunt 2. It is much cleaner and safer than Carcer City from Manhunt 1. It has suburbs and Downtown with a thriving economy though the city has large amounts of crime as well. Cities like Atlanta, Tampa, New Orleans, and Detroit inspired the city. In 2006-2007 Cottonmouth continues with a good economy, but in 2012-1013, the city is much darker and scary due to many asylum prisoners escaping.